• Dr. Imran Khan
  • Experience

    Designation Service Type From To
    Assistant Professor BPS Aug 16, 2022 Aug 15, 2022
    Assistant Professor TTS Mar 9, 2022 Aug 15, 2022
    Contract Jul 18, 2016 Aug 31, 2021
    Research Assistant Contract Mar 7, 2011 Nov 3, 2011
  • Biblography

    Assistant Professor (at Abdul Wali Khan University Mardan) 16 Aug 2022 -Continue Assistant Professor (at University of Malaysia Sabah) 11 May 2022 – 15 Aug 2022 At University of Malaysia, Dr. Khan was required to allocate 30% of his time to teaching and 70% to research. At this point time, he planned to explore the anti-obesogenic effects of natural compounds in pre-clinical animal models. He prospected to investigate the anti-cancer properties of various bio-active natural compounds. Post-doctoral Fellow (Under Global Talent Program by Macau Government) Sep 2019 – Aug 2021 Dr. Khan was awarded fellowship under the global talent program by Macau government. He joined Prof. Wendy’s lab which was determining the peanut allergy causes at microbial level. He contributed to the development of a pre-clinical model for peanut allergy. Through 16S amplicon sequencing and modern culturomics techniques, he identified a single bacterium that was the main culprit behind peanut allergy development. Through heuristic wet and dry lab experiments, he also contributed to determine one herbal compound and two potential probiotic bacterial species that alleviated anaphylactic symptoms in the mouse model. In addition, he was engaged in another project that was focused to examine the anti-aging properties of icariin (an herbal compound) at the interface of gut microbiome. Besides, he was collaborating with other colleagues by mining BIG DATA for identifying potential clinical markers as a target for drug and diagnostics. Post-doctoral Fellow (Supported by FDCT of Macau Government) Jul 2016 – Aug 2019 Dr. Khan was hired by Prof. Wendy to determine the microbial causes in colorectal cancer development and progression, where he profiled microbiome composition of different knock out mouse model for cancer (APCMin/+, KRAS, P53). He helped in screening various herbal compounds and other TCM formulae to fix the dysbiotic gut microbial composition. He identified several polysaccharides, ginsenosides, flavonoids, and saponins that possessed the ability to fix the disturbed microbial composition and resulted in lowering polyp burden in pre-clinical mouse model. Research Associate (Employer NIBGE, PIEAS, Pakistan) Mar – Nov 2011 He was selected as a Research Associate at the National Institute for Biotechnology and Genetic Engineering, PIEAS, Pakistan. He was stationed in the Industrial Biotechnology Division and was tasked to develop mutant fungal strains for mass-level enzyme production for industrial application.
  • Research Publications

    S.No: Title
    1 Nutrition to support gut health and the microbiome in athletes. Frontiers in Nutrition.
    2 Traditional Patchouli Essential Oil modulates the host’s immune responses and gut microbiota and exhibits potent anti-cancer effects in ApcMin/+ mice.
    3 Icariin enhances youth-like features by attenuating the declined gut microbiota in the aged mice.
    4 Bifidobacterium animalis - the missing link for the cancer-preventive effect of Gynostemma pentaphyllum
    5 Adaptogenic flower buds exert cancer-preventive effects by enhancing the SCFA-producers, strengthening the epithelial tight junction complex and immune responses.
    6 Fructo-oligosaccharides from Morinda officinalis remodeled gut microbiota and alleviated depression features in a stress rat model.
    7 Far infrared radiation induces changes in gut microbiota and activates host’s GPCRs in mice.
    8 Mushroom polysaccharides and jiaogulan saponins exert cancer preventive effects by shaping the gut microbiota and microenvironment in ApcMin/+ mic
    9 Mushroom polysaccharides from Ganoderma lucidum and Poria cocos reveal prebiotic functions
    10 Ginsenosides Rb3 and Rd reduce polyps formation while reinstate the dysbiotic gut microbiota and the intestinal microenvironment in ApcMin/+ mice
    11 Exploring the role of gut microbiota in advancing personalized medicine
    12 Drugs and gut microbiome interactions—an emerging field of tailored medicine.
    13 Bacterial polysaccharides–a big source for prebiotics and therapeutics
    14 Poria cocos polysaccharides exert prebiotic function to attenuate the adverse effects and improve the therapeutic outcome of 5-FU in ApcMin/+ mice
    15 Novel clinical biomarkers in blood and pleural effusion for diagnosing patients with tuberculosis distinguishing from malignant tumor
    16 Poria cocos polysaccharides exert prebiotic function to attenuate the adverse effects and improve the therapeutic outcome of 5-FU in ApcMin/+ mice.
    17 Kaempferol acts on bile acid signaling and gut microbiota to attenuate the tumor burden in ApcMin/+ mice
    18 Prebiotic properties of jiaogulan in the context of gut microbiome
    19 Changes in the gut microbiota of morbidly obese patients after laparoscopic sleeve gastrectomy
    20 Khan SB. Emerging Fabrication Strategies of Hydrogels and Its Applications
    21 Bacterial diversity and the antimicrobial resistome in the southwestern highlands of Saudi Arabia
    22 Novel clinical biomarkers in blood and pleural effusion for diagnosing patients with tuberculosis distinguishing from malignant tumour
    23 Recent progress in the development of potential drugs against SARS-CoV-2
    24 Saponins isolated from Radix polygalae extent lifespan by modulating complement C3 and gut microbiota.
    25 Ginseng polysaccharides alter the gut microbiota and kynurenine/tryptophan ratio, potentiating the anti-tumor effect of anti-programmed cell death 1 /programmed cell death ligand 1 (anti-PD-1/PD-L1) immunotherapy
    26 Groundwater quality and potential health risks caused by arsenic (As) in Bhakkar, Pakistan
    27 Clinical significance of LSECtin and its association with PVR in non-small-cell lung cancer patients.
    28 Lycium berry polysaccharides strengthen gut microenvironment and modulated gut microbiota of the mice
    29 Prognostic significance of tumor poliovirus receptor and CTLA4 expression in patients with surgically resected non-small-cell lung cancer.
    30 Correlation of gut microbial compositions to the development of Kawasaki disease vasculitis in children
  • Awards

    Organization Description Date
    USERN Nominee for the emerging scientist prize of 2024 Apr 21, 2024
    Government of Macau Global Talent Fellowship Sep 6, 2020
  • Conferences

    Level Country City Conference Dated
    International Hong Kong Hong Kong Hong Kong Biotech Horizon - 2018 Sep 19, 2018
    International Malaysia Kuching Consortium for Globalization of Chinese Medicine (CGCM-17) Aug 8, 2018
    International China Beijing 2016 World life science conferences Nov 7, 2016
    International Pakistan Islamabad 7th one day workshop on the significance of bioinformatics in life sciences May 7, 2016
    International Saudi Arabia Jeddah 5th Scientific Forum for Student of Faculty of Science Nov 9, 2014
    International Saudi Arabia Jeddah Second International Genomic Medicine Conference Nov 21, 2013
    International China Nanning The 2nd council election meeting and 5th annual meeting of specialty committee of immunology of t Nov 9, 2018
    International Saudi Arabia Thuwal CBRC, King Abdullah University of Science and Technology Dec 15, 2016
    International Pakistan Kashmir Prospects and Challenges to Sustainable Agriculture” organized by the Faculty of Agriculture, Univer Jul 12, 2012
  • Memberships

    Title Organization From Date To Dated
    Imran Khan (2003095) American Society for Microbiology (ASM) Jan 1, 2022 Dec 31, 2022
  • Fundings

    Title Type Source From Date To Date
    Analysis of Gut Microbiome in Multi-Drug Resistant Strains Infected Human and Mice Model Research King Abdullah City of Science and Technology, Saudi Arabia May 30, 2013 Apr 30, 2015
  • Social Accounts

    Title Link
    ORCiD Click to View
    GoogleScholar Click to View
    Facebook Click to View
Stats Tab Content

General Settings

Some information about this general settings option

Other sets of options are available

Allow the user to show his name in blog posts

Chat Settings

Success!